Last Updated: January 29, 2021
There were a total of 7 head coaching changes this off-season.
| Team | Conf | 2020 Coach | Year | Latest Status | 2021 Coach |
|---|---|---|---|---|---|
| ARI | N | Kliff Kingsbury | 2nd | Kliff Kingsbury | |
| ATL | N | Dan Quinn | 6th | Quinn and GM Thomas Dimitroff fired on 10/11/2020 after going 0-5; DC Raheem Morris is interim. TEN OC Arthur Smith hired on 01/15/2021. | Arthur Smith |
| BAL | A | John Harbaugh | 13th | John Harbaugh | |
| BUF | A | Sean McDermott | 4th | Sean McDermott | |
| CAR | N | Matt Rhule | 1st | Matt Rhule | |
| CHI | N | Matt Nagy | 3rd | Matt Nagy | |
| CIN | A | Zac Taylor | 2nd | Zac Taylor | |
| CLE | A | Kevin Stefanski | 1st | Kevin Stefanski | |
| DAL | N | Mike McCarthy | 1st | Mike McCarthy | |
| DEN | A | Vic Fangio | 2nd | Vic Fangio | |
| DET | N | Matt Patricia | 3rd | Patricia and GM Bob Quinn fired on 11/28/2020 after going 4-7; OC Darrell Bevell is interim. NO AHC Dan Campbell hired on 01/20/2021. | Dan Campbell |
| GB | N | Matt LaFleur | 2nd | Matt LaFleur | |
| HOU | A | Bill O'Brien | 7th | O'Brien fired on 10/05/2020 after going 0-4; AHC Romeo Crennel is interim. BAL AHC David Culley hired on 01/28/2021. | David Culley |
| IND | A | Frank Reich | 3rd | Frank Reich | |
| JAC | A | Doug Marrone | 5th | Marrone fired on 01/04/2021. Former OSU head coach Urban Meyer hired on 01/14/2021. | Urban Meyer |
| KC | A | Andy Reid | 8th | Andy Reid | |
| LV | A | Jon Gruden | 3rd | Jon Gruden | |
| LAC | A | Anthony Lynn | 4th | Lynn fired on 01/04/2021. LAR DC Brandon Staley hired on 01/17/2021. | Brandon Staley |
| LAR | A | Sean McVay | 4th | Sean McVay | |
| MIA | A | Brian Flores | 2nd | Brian Flores | |
| MIN | N | Mike Zimmer | 7th | Mike Zimmer | |
| NE | A | Bill Belichick | 21st | Bill Belichick | |
| NO | N | Sean Payton | 15th | Sean Payton | |
| NYG | N | Joe Judge | 1st | Joe Judge | |
| NYJ | A | Adam Gase | 2nd | Gase fired on 01/03/2021 SF DC Robert Saleh hired on 01/14/2021. | Robert Saleh |
| PHI | N | Doug Pederson | 5th | Pederson fired on 01/11/2021. IND OC Nick Sirianni hired on 01/24/2021. | Nick Sirianni |
| PIT | A | Mike Tomlin | 14th | Mike Tomlin | |
| SF | N | Kyle Shanahan | 4th | Kyle Shanahan | |
| SEA | N | Pete Carroll | 11th | Pete Carroll | |
| TB | N | Bruce Arians | 2nd | Bruce Arians | |
| TEN | A | Mike Vrabel | 3rd | Mike Vrabel | |
| WAS | N | Ron Rivera | 1st | Ron Rivera |